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The route from Milan to Rome is served daily by 175 trains leaving from from the stations of Milano Centrale, Milano Rog, Milano Porta Garibaldi, Milano Rho Fiera and arriving at in the stations of Roma Termini, Roma Tiburtina, Roma Ostiense.
The average journey duration is 3 h 25 min. The first train leaves at 5:00am. The last one is at 11:17pm.

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