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The route from Rome to Milan is served daily by 178 trains leaving from from the stations of Roma Ostiense, Roma Termini, Roma Tiburtina and arriving at in the stations of Milano Centrale, Milano Rho Fiera, Milano Rog, Milano Porta Garibaldi.
The average journey duration is 3 h 23 min. The first train leaves at 12:11am. The last one is at 11:55pm.

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