If the offers provided by buses do not suit your needs, trains and carpooling could represent a good alternative for this distance.
If you are looking for different alternatives to travel from Rome to Milan, trains and carpooling solutions could be a good deal seen the relatively short distance.
Travelling by bus to Milan from Rome: how many daily connections are there?
If you desire to go to Milan from Rome by bus, 56 daily connections are available. Please note that 36 routes include one change or more whereas 20 routes are direct lines. Therefore, choosing a trip including a change is sometimes more efficient although it is longer especially if there are too few connections and if you look for a ticket at the last minute. However, considering choosing a ticket for a direct line seems to be the best option if your priority is to stay in the same bus for the whole trip.
What time are the buses to Milan?
The first bus to Milan leaves at 01:03, while the last one is scheduled at 23:10. The journey takes on average 11 hours and 14 minutes, but the fastest connections take only 9 hours and 35 minutes.
Which bus companies serve the route Rome - Milan?
Virail counts among its partners also FlixBus and Marino, with buses from Rome to Milan.
Flixbus is undoubtedly one of the youngest and most famous bus companies in whole Europe. With more than 40 millions passengers only in 2017, Flixbus offers national and international bus connections, also with night buses.
Marino is an Italian company mostly active in Southern Italy, but providing bus connections driving up to Northern Italy and also to France, Switzerland and Germany.