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The route from Pisa to Rome is served daily by 57 trains leaving from from the stations of Pisa Centrale, Pisa S. Rossore and arriving at in the stations of Roma Ostiense, Roma Termini, Roma Tiburtina.
The average journey duration is 3 h 14 min. The first train leaves at 4:26am. The last one is at 8:48pm.

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