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The route from Pisa to Milan is served daily by 51 trains leaving from from the stations of Pisa Centrale, Pisa S. Rossore and arriving at in the stations of Milano Centrale, Milano Rogoredo, Milano Porta Genova, Milano Porta Venezia.
The average journey duration is 4 h 4 min. The first train leaves at 3:26am. The last one is at 8:38pm.

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