If the offers provided by buses do not suit your needs, trains and carpooling could represent a good alternative for this distance.
With such a long journey, we would like to give you some advice: you can look for a flight to Barcelona, or if your budget is limited, you can check night buses and trains to save the daytime for your visits.
When do the first and last buses from Prague to Barcelona leave?
To get to Barcelona from Prague by bus, it will take you around 36 hours and 27 minutes, or even 34 hours and 10 minutes if you choose the fastest solutions. The first bus leaves Prague at 13:03, while the last one is at 22:03.
Which bus companies serve the route Prague - Barcelona?
With Eurolines SA and Eurolines you will be able to travel trom Prague to Barcelona by bus.
Eurolines is one of the leader bus companies in Europe, with more than 350 connections in 23 countries. Among its services you can also find long-distance night buses.