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Prague to Rome Bus

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11/13/2025
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Prague to Rome by bus

The journey from Prague to Rome by bus is 574.27 mi and takes 24 hr 53 min. There are 124 connections per day, with the first departure at 2:30 AM and the last at 11:50 PM. It is possible to travel from Prague to Rome by bus for as little as $46.72 or as much as $210.15. The best price for this journey is $46.72.

Lowest Price $46.72
Journey Duration 24 hr 53 min
Connection per Day 124
Lowest Price $46.72
Highest Price $210.15
First Departure 2:30 AM
Last Departure 11:50 PM
Distance 574.27 mi
Departure Prague
Arrival Rome
Carriers RegioJet, FlixBus

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Price as departure date approaches

Bus companies may charge higher ticket prices as the date of departure approaches. Prices in the next days can range from around $64.91 to $91.70 but may be subject to change. Our advice is to book as early as possible to potentially save up to 29% on your trip!

Best time to book cheap bus tickets from Prague to Rome

The cheapest Prague - Rome bus tickets can be found for as low as $66.12 if you’re lucky, or $78.43 on average. The most expensive ticket can cost as much as $100.35.

Find the best day to travel to Rome by bus

When travelling to Rome by bus, if you want to avoid crowds you can check how frequently our customers are travelling in the next 30-days using the graph below. On average, the peak hours to travel are between 6:30am and 9am in the morning, or between 4pm and 7pm in the evening. Please keep this in mind when travelling to your point of departure as you may need some extra time to arrive, particularly in big cities!

Services on board RegioJet and FlixBus from Prague to Rome
Compare services on board when travelling from Prague to Rome by bus.
Facilities RegioJet FlixBus
quiet_zone Quiet zone check cross
wifi WiFi check check
power_sockets Power sockets check check
luggage Luggage check check
accessibility Accessibility check check
food_and_drink Food and drink check check
air_con Air conditioning check check
bicycle Bicycle check check
entertainment_portal Entertainment Portal cross check
mobility_and_wheelchair_services landingPage.services.mobility_and_wheelchair_services cross check

Prague to Rome CO2 Emissions by Bus

Ecology
Train
64.69kg
Bus
69.32kg
Flight
184.84kg
Car
147.87kg

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Frequently Asked Questions

How much is a bus ticket from Prague to Rome?
A bus ticket from Prague to Rome is $101.45. However the price varies depending on how early you buy, and if it's peak time to travel. Occasionally you can find them for as cheap as $46.72.
What's the cheapest bus ticket from Prague to Rome?
The cheapest ticket you can get from Prague to Rome is $46.72. We recommend booking as early as possible and off-peak hours to get the cheapest ticket possible. Off-peak times are usually from 09:30 to 16:00, and after 19:00.
What's the distance between Prague and Rome by bus?
Prague to Rome is 574.27 mi.
How long does the bus between Prague and Rome take?
Prague to Rome is on average 24 hr 53 min. However the fastest option will get you there in 19 hr 30 min.
Which companies operate from Prague to Rome?
The bus journey from Prague to Rome is covered by 1 operator(s). On Virail you can find these carriers that provide services on this route: RegioJet and FlixBus.
How many bus connections per day go from Prague to Rome?
Prague to Rome has 124 connection(s) per day on average.
What time does the first bus from Prague to Rome leave?
The earliest bus from Prague to Rome departs at 2:30 AM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
What time does the last bus from Prague to Rome depart?
The latest bus from Prague to Rome departs at 11:50 PM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
Should I book my ticket from Prague to Rome in advance?
If you can, we recommend booking your ticket as early as possible to ensure you get better savings. The cheapest bus ticket we have found is $46.72 but this may be subject to change depending on the day of travel, hour you wish to depart and how far in advance you book.
How many direct connections depart from Prague to Rome?
There are on average 5 direct connection(s) from Prague to go to Rome.
What's the fastest journey time between Prague to Rome by bus?
The fastest journey time by bus between Prague and Rome is 19 hr 30 min.
Is there a direct bus from Prague to Rome?
Yes, there is a direct bus between Prague and Rome.
What are the CO2 emissions for Prague to Rome by bus?
The bus journey from Prague to Rome creates 69.32kg of CO2 emissions.

Go local from Prague

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