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The route from Prague to Cologne is served daily by 21 bus departing from the stations of Prague Main Railway Station, Prague ÚAN Florenc, Prague ,Hradčanská and arriving to the stations of Cologne South, Airport, Cologne North, Leverkusen, Cologne East, Refrath.
The average duration of the journey is 14 h 15 min. The first bus leaves at 12:05am.

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