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Milan to Palermo Bus

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06/21/2025
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Milan to Palermo by bus

The journey from Milan to Palermo by bus is 551.72 mi and takes 25 hr 33 min. There are 39 connections per day, with the first departure at 3:15 AM and the last at 11:50 PM. It is possible to travel from Milan to Palermo by bus for as little as $47.41 or as much as $208.97. The best price for this journey is $47.41.

Lowest Price $47.41
Journey Duration 25 hr 33 min
Connection per Day 39
Lowest Price $47.41
Highest Price $208.97
First Departure 3:15 AM
Last Departure 11:50 PM
Distance 551.72 mi
Departure Milan
Arrival Palermo
Carriers Autoservizi Salemi, FlixBus

Milan to Palermo Bus Times

Departure date
Saturday, Jun 21, 2025

Compare prices and tickets from Milan to Palermo

Best time to book Milan to Palermo travel

Virail Pro Tip ✌: Booking 10 days in advance save 10% on average

Price as departure date approaches

Bus companies may charge higher ticket prices as the date of departure approaches. Prices in the next days can range from around $28.19 to $142.44 but may be subject to change. Our advice is to book as early as possible to potentially save up to 80% on your trip!

Best time to book cheap bus tickets from Milan to Palermo

The cheapest Milan - Palermo bus tickets can be found for as low as $46.92 if you’re lucky, or $74.53 on average. The most expensive ticket can cost as much as $90.19.

Find the best day to travel to Palermo by bus

When travelling to Palermo by bus, if you want to avoid crowds you can check how frequently our customers are travelling in the next 30-days using the graph below. On average, the peak hours to travel are between 6:30am and 9am in the morning, or between 4pm and 7pm in the evening. Please keep this in mind when travelling to your point of departure as you may need some extra time to arrive, particularly in big cities!

Services on board Autoservizi Salemi, FlixBus and Marino Bus from Milan to Palermo
Compare services on board when travelling from Milan to Palermo by bus.
Facilities Autoservizi Salemi FlixBus Marino Bus
wifi WiFi check check check
power_sockets Power sockets check check check
food_and_drink Food and drink check check check
air_con Air conditioning check check check
luggage Luggage cross check check
accessibility Accessibility cross check check
bicycle Bicycle cross check cross
entertainment_portal Entertainment Portal cross check cross
mobility_and_wheelchair_services landingPage.services.mobility_and_wheelchair_services cross check cross

Milan to Palermo CO2 Emissions by Bus

Ecology
Train
62.15kg
Bus
66.59kg
Flight
177.58kg
Car
142.07kg

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Frequently Asked Questions

How much is a bus ticket from Milan to Palermo?
A bus ticket from Milan to Palermo is $90.99. However the price varies depending on how early you buy, and if it's peak time to travel. Occasionally you can find them for as cheap as $47.41.
What's the cheapest bus ticket from Milan to Palermo?
The cheapest ticket you can get from Milan to Palermo is $47.41. We recommend booking as early as possible and off-peak hours to get the cheapest ticket possible. Off-peak times are usually from 09:30 to 16:00, and after 19:00.
What's the distance between Milan and Palermo by bus?
Milan to Palermo is 551.72 mi.
How long does the bus between Milan and Palermo take?
Milan to Palermo is on average 25 hr 33 min. However the fastest option will get you there in 21 hr 0 min.
Which companies operate from Milan to Palermo?
The bus journey from Milan to Palermo is covered by 2 operator(s). On Virail you can find these carriers that provide services on this route: Autoservizi Salemi, FlixBus and Marino Bus.
How many bus connections per day go from Milan to Palermo?
Milan to Palermo has 39 connection(s) per day on average.
What time does the first bus from Milan to Palermo leave?
The earliest bus from Milan to Palermo departs at 3:15 AM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
What time does the last bus from Milan to Palermo depart?
The latest bus from Milan to Palermo departs at 11:50 PM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
Should I book my ticket from Milan to Palermo in advance?
If you can, we recommend booking your ticket as early as possible to ensure you get better savings. The cheapest bus ticket we have found is $47.41 but this may be subject to change depending on the day of travel, hour you wish to depart and how far in advance you book.
How many direct connections depart from Milan to Palermo?
There are on average 2 direct connection(s) from Milan to go to Palermo.
What's the fastest journey time between Milan to Palermo by bus?
The fastest journey time by bus between Milan and Palermo is 21 hr 0 min.
Is there a direct bus from Milan to Palermo?
Yes, there is a direct bus between Milan and Palermo.
What are the CO2 emissions for Milan to Palermo by bus?
The bus journey from Milan to Palermo creates 66.59kg of CO2 emissions.

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