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The route from Frankfurt to Berlin is served daily by 404 trains leaving from from the stations of Frankfurt(M)Ostendstraße, Leipzig Hbf, Frankfurt(M)Hauptwache, Leipzig Hbf (tief), Frankfurt(M)Konstablerwache and arriving at in the stations of Berlin-Spandau, Berlin-Spandau (S), Berlin Gesundbrunnen, Berlin Ostbahnhof (S), Berlin Hbf (tief), Berlin Südkreuz, Berlin Hbf, Berlin Ostbahnhof, Berlin Gesundbrunnen(S).
The average journey duration is 4 h 2 min. The first train leaves at 4:51am. The last one is at 11:20pm.

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