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The route from Palermo to Rome is served daily by 4 bus departing from the stations of Piazza Ruggero Settimo, 12, Piazza Cairoli, 8 and arriving to the station of Via Tiburtina.
The average duration of the journey is 13 h 41 min. The first bus leaves at 5:30pm. The last is at 6:00pm.

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