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The route from Florence to Milan is served daily by 84 bus departing from the stations of Florence (Piazzale Montelungo), Florence (Villa Costanza Tram T1), Nord Autostazione, Terminal Bus Villa Constanza, Capolinea Tramvia Villa Costanza and arriving to the stations of Milan (Lampugnano), Bergamo (Orio Al Serio Airport - BGY), Malpensa Terminal 1, Milan (San Donato), San Donato, Lampugnano, Milano Rogoredo, Via Giulio Natta, 32, Milano (Sesto S.G.), Malpensa Terminal 2.
The average duration of the journey is 5 h 15 min. The first bus leaves at 12:05am. The last is at 11:41pm.

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