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The route from Florence to Messina is served daily by 60 trains leaving from from the stations of Firenze S. M. Novella, Firenze Campo Di Marte, Firenze Rifredi and arriving at in the stations of Messina Marittima, Tremestieri, Ponte Schiavo, Messina Centrale, Fiumara Gazzi.
The average journey duration is 10 h 59 min. The first train leaves at 5:45am. The last one is at 9:57pm.

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