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The route from Cologne to Brussels is served daily by 16 bus departing from the stations of Cologne South, Airport, Cologne / Bonn Airport Busterminal, Cologne North, Leverkusen and arriving to the stations of Brussels-North Station, Brussels North Train Station, Brussels Airport, Brussels Zaventem Airport, Brussels South (Gare Du Midi).
The average duration of the journey is 3 h 54 min. The first bus leaves at 1:40am. The last is at 11:10pm.

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