All Great Journeys Start With A Map 🌎 Try DOTS for free
Virail Logo

Santander to Madrid Bus

the dotted world map
06/23/2025
+ Add return
Stay with Booking.com

Download our App for free

Find the cheapest ticket for your trip

Secure your ticket today and get the best deals!

Today $36.16
Tomorrow More
2 days More
3 days More

Santander to Madrid by bus

The journey from Santander to Madrid by bus is 210.91 mi and takes 9 hr 45 min. There are 16 connections per day, with the first departure at 12:45 AM and the last at 6:50 PM. It is possible to travel from Santander to Madrid by bus for as little as $36.16 or as much as $152.01. The best price for this journey is $36.16.

Lowest Price $36.16
Journey Duration 9 hr 45 min
Connection per Day 16
Lowest Price $36.16
Highest Price $152.01
First Departure 12:45 AM
Last Departure 6:50 PM
Distance 210.91 mi
Departure Santander
Arrival Madrid
Carriers FlixBus, Alsa

Santander to Madrid Bus Times

Departure date
Monday, Jun 23, 2025

Compare prices and tickets from Santander to Madrid

Best time to book Santander to Madrid travel

Virail Pro Tip ✌: Booking 10 days in advance save 10% on average

Price as departure date approaches

Bus companies may charge higher ticket prices as the date of departure approaches. Prices in the next days can range from around $22.45 to $39.47 but may be subject to change. Our advice is to book as early as possible to potentially save up to 43% on your trip!

Best time to book cheap bus tickets from Santander to Madrid

The cheapest Santander - Madrid bus tickets can be found for as low as $32.67 if you’re lucky, or $35.61 on average. The most expensive ticket can cost as much as $41.64.

Find the best day to travel to Madrid by bus

When travelling to Madrid by bus, if you want to avoid crowds you can check how frequently our customers are travelling in the next 30-days using the graph below. On average, the peak hours to travel are between 6:30am and 9am in the morning, or between 4pm and 7pm in the evening. Please keep this in mind when travelling to your point of departure as you may need some extra time to arrive, particularly in big cities!

Services on board FlixBus and Alsa from Santander to Madrid
Compare services on board when travelling from Santander to Madrid by bus.
Facilities FlixBus Alsa
power_sockets Power sockets check check
luggage Luggage check check
food_and_drink Food and drink check check
air_con Air conditioning check check
wifi WiFi check check
accessibility Accessibility check check
bicycle Bicycle check check
entertainment_portal Entertainment Portal check cross
mobility_and_wheelchair_services landingPage.services.mobility_and_wheelchair_services check cross

Santander to Madrid CO2 Emissions by Bus

Ecology
Train
23.76kg
Bus
25.46kg
Flight
67.89kg
Car
54.31kg

Anything we can improve?

Frequently Asked Questions

How much is a bus ticket from Santander to Madrid?
A bus ticket from Santander to Madrid is $69.00. However the price varies depending on how early you buy, and if it's peak time to travel. Occasionally you can find them for as cheap as $36.16.
What's the cheapest bus ticket from Santander to Madrid?
The cheapest ticket you can get from Santander to Madrid is $36.16. We recommend booking as early as possible and off-peak hours to get the cheapest ticket possible. Off-peak times are usually from 09:30 to 16:00, and after 19:00.
What's the distance between Santander and Madrid by bus?
Santander to Madrid is 210.91 mi.
How long does the bus between Santander and Madrid take?
Santander to Madrid is on average 9 hr 45 min. However the fastest option will get you there in 5 hr 0 min.
Which companies operate from Santander to Madrid?
The bus journey from Santander to Madrid is covered by 1 operator(s). On Virail you can find these carriers that provide services on this route: FlixBus and Alsa.
How many bus connections per day go from Santander to Madrid?
Santander to Madrid has 16 connection(s) per day on average.
What time does the first bus from Santander to Madrid leave?
The earliest bus from Santander to Madrid departs at 12:45 AM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
What time does the last bus from Santander to Madrid depart?
The latest bus from Santander to Madrid departs at 6:50 PM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
Should I book my ticket from Santander to Madrid in advance?
If you can, we recommend booking your ticket as early as possible to ensure you get better savings. The cheapest bus ticket we have found is $36.16 but this may be subject to change depending on the day of travel, hour you wish to depart and how far in advance you book.
How many direct connections depart from Santander to Madrid?
There are on average 12 direct connection(s) from Santander to go to Madrid.
What's the fastest journey time between Santander to Madrid by bus?
The fastest journey time by bus between Santander and Madrid is 5 hr 0 min.
Is there a direct bus from Santander to Madrid?
Yes, there is a direct bus between Santander and Madrid.
What are the CO2 emissions for Santander to Madrid by bus?
The bus journey from Santander to Madrid creates 25.46kg of CO2 emissions.

Go local from Santander

Buses Santander - BilbaoBuses Santander - San Sebastián / DonostiaBuses Santander - IrunBuses Santander - Miranda de EbroBuses Santander - BiarritzBuses Santander - ZarautzBuses Santander - ReinosaBuses Santander - RibadeoBuses Santander - LeónBuses Santander - San Vicente de la BarqueraBuses Santander - Valladolid

Trending routes

Buses Santander - BarcelonaBuses Santander - SevilleBuses Santander - SaragossaBuses Santander - VigoBuses Santander - San Sebastián / DonostiaBuses Santander - SalamancaBuses Santander - PontevedraBuses Santander - IrunBuses Santander - MéridaBuses Santander - Miranda de EbroBuses Santander - ValladolidBuses Santander - Bilbao

Weekend getaways from Santander

Buses Santander - MéridaBuses Santander - SaragossaBuses Santander - VigoBuses Santander - PontevedraBuses Santander - BarcelonaBuses Santander - SalamancaBuses Santander - Seville

International routes from Santander and nearby areas

Buses Santander - BiarritzBuses Irun - ParisBuses Biarritz - ParisBuses Bilbao - ReimsBuses Bilbao - PerpignanBuses Bilbao - EvoraBuses Bilbao - BayonneBuses Biarritz - BayonneBuses Irun - GuimarãesBuses Bilbao - PortimaoBuses Valladolid - ChavesBuses Biarritz - Lourdes, Occitania

Other destinations from Santander

Buses Santander - IrunBuses Santander - VigoBuses Santander - SalamancaBuses Santander - ZarautzBuses Santander - Miranda de EbroBuses Santander - ReinosaBuses Santander - PontevedraBuses Santander - BilbaoBuses Santander - San Vicente de la BarqueraBuses Santander - SevilleBuses Santander - ValladolidBuses Santander - León

Main routes to Madrid

Buses Vigo - MadridBuses Valencia - MadridBuses Vitoria-Gasteiz - MadridBuses Saragossa - MadridBuses Almería - MadridBuses San Sebastián / Donostia - MadridBuses Reus - MadridBuses Albacete - MadridBuses Logroño - MadridBuses Bilbao - MadridBuses Ourense - MadridBuses Gijón - Madrid

Related routes

Trains Santander - MadridFlight Santander - MadridTrains Madrid - SantanderBuses Madrid - SantanderFlight Madrid - Santander

Other popular routes

Buses Padua - TurinBuses Padua - BolzanoBuses Bologna - MessinaBuses Milan - GoriziaBuses Taranto - NaplesBuses Ostuni - RomeBuses Brescia - ParmaBuses Bergamo - BariBuses Fermo - RomeBuses Bolzano - NaplesBuses Parma - MilanBuses Turin - BresciaBuses Brescia - TurinBuses Catania - RomeBuses Valencia - VigoBuses Bari - BolzanoBuses Brescia - Peschiera del GardaBuses Palermo - VeronaBuses Bologna - PerugiaBuses Naples - Peschiera del Garda