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The route from La Spezia to Milan is served daily by 81 trains leaving from from the stations of La Spezia Centrale, La Spezia Migliarina, Ca' Di Boschetti and arriving at in the stations of Milano Centrale, Milano Rogoredo, Milano Porta Garibaldi.
The average journey duration is 4 h. The first train leaves at 1:00am. The last one is at 8:16pm.

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