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Jackson, MS to Chicago, IL Bus

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11/17/2025
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Jackson, MS to Chicago, IL by bus

The journey from Jackson, MS to Chicago, IL by bus is 675.22 mi and takes 22 hr 11 min. There are 11 connections per day, with the first departure at 12:10 PM and the last at 6:25 PM. It is possible to travel from Jackson, MS to Chicago, IL by bus for as little as $79.98 or as much as $298.84. The best price for this journey is $79.98.

Lowest Price $79.98
Journey Duration 22 hr 11 min
Connection per Day 11
Lowest Price $79.98
Highest Price $298.84
First Departure 12:10 PM
Last Departure 6:25 PM
Distance 675.22 mi
Departure Jackson, MS
Arrival Chicago, IL
Carriers Greyhound, Greyhound Lines, Inc.

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Best time to book cheap bus tickets from Jackson, MS to Chicago, IL

The cheapest Jackson, MS - Chicago, IL bus tickets can be found for as low as $72.88 if you’re lucky, or $131.11 on average. The most expensive ticket can cost as much as $209.05.

Find the best day to travel to Chicago, IL by bus

When travelling to Chicago, IL by bus, if you want to avoid crowds you can check how frequently our customers are travelling in the next 30-days using the graph below. On average, the peak hours to travel are between 6:30am and 9am in the morning, or between 4pm and 7pm in the evening. Please keep this in mind when travelling to your point of departure as you may need some extra time to arrive, particularly in big cities!

Services on board Greyhound and FlixBus from Jackson, MS to Chicago, IL
Compare services on board when travelling from Jackson, MS to Chicago, IL by bus.
Facilities Greyhound FlixBus
wifi WiFi check check
power_sockets Power sockets check check
luggage Luggage check check
air_con Air conditioning check check
accessibility Accessibility check check
food_and_drink Food and drink cross check
bicycle Bicycle cross check
entertainment_portal Entertainment Portal cross check
mobility_and_wheelchair_services landingPage.services.mobility_and_wheelchair_services cross check

Jackson, MS to Chicago, IL CO2 Emissions by Bus

Ecology
Train
76.07kg
Bus
81.5kg
Flight
217.33kg
Car
173.87kg

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Frequently Asked Questions

How much is a bus ticket from Jackson, MS to Chicago, IL?
A bus ticket from Jackson, MS to Chicago, IL is $162.39. However the price varies depending on how early you buy, and if it's peak time to travel. Occasionally you can find them for as cheap as $79.98.
What's the cheapest bus ticket from Jackson, MS to Chicago, IL?
The cheapest ticket you can get from Jackson, MS to Chicago, IL is $79.98. We recommend booking as early as possible and off-peak hours to get the cheapest ticket possible. Off-peak times are usually from 09:30 to 16:00, and after 19:00.
What's the distance between Jackson, MS and Chicago, IL by bus?
Jackson, MS to Chicago, IL is 675.22 mi.
How long does the bus between Jackson, MS and Chicago, IL take?
Jackson, MS to Chicago, IL is on average 22 hr 11 min. However the fastest option will get you there in 14 hr 45 min.
Which companies operate from Jackson, MS to Chicago, IL?
The bus journey from Jackson, MS to Chicago, IL is covered by 2 operator(s). On Virail you can find these carriers that provide services on this route: Greyhound, Greyhound Lines, Inc. and FlixBus.
How many bus connections per day go from Jackson, MS to Chicago, IL?
Jackson, MS to Chicago, IL has 11 connection(s) per day on average.
What time does the first bus from Jackson, MS to Chicago, IL leave?
The earliest bus from Jackson, MS to Chicago, IL departs at 12:10 PM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
What time does the last bus from Jackson, MS to Chicago, IL depart?
The latest bus from Jackson, MS to Chicago, IL departs at 6:25 PM. However be sure to check with us the schedule on the day you want to leave as the time may differ.
Should I book my ticket from Jackson, MS to Chicago, IL in advance?
If you can, we recommend booking your ticket as early as possible to ensure you get better savings. The cheapest bus ticket we have found is $79.98 but this may be subject to change depending on the day of travel, hour you wish to depart and how far in advance you book.
What's the fastest journey time between Jackson, MS to Chicago, IL by bus?
The fastest journey time by bus between Jackson, MS and Chicago, IL is 14 hr 45 min.
Is there a direct bus from Jackson, MS to Chicago, IL?
Yes, there is a direct bus between Jackson, MS and Chicago, IL.
What are the CO2 emissions for Jackson, MS to Chicago, IL by bus?
The bus journey from Jackson, MS to Chicago, IL creates 81.5kg of CO2 emissions.

Go local from Jackson, MS

Buses Jackson, MS - Baton Rouge, LABuses Jackson, MS - Mobile, ALBuses Jackson, MS - Hattiesburg, MSBuses Jackson, MS - Meridian, MS

Trending routes

Buses Jackson, MS - Houston, TXBuses Jackson, MS - Dallas, TXBuses Jackson, MS - Los Angeles, CABuses Jackson, MS - Phoenix, AZBuses Jackson, MS - Boston, MABuses Jackson, MS - Atlanta, GABuses Jackson, MS - Orlando, FLBuses Jackson, MS - Denver, COBuses Jackson, MS - Oklahoma City, OKBuses Jackson, MS - Kansas City, MOBuses Jackson, MS - Baton Rouge, LABuses Jackson, MS - Shreveport, LA

Weekend getaways from Jackson, MS

Buses Jackson, MS - Houston, TXBuses Jackson, MS - Dallas, TXBuses Jackson, MS - Oklahoma City, OKBuses Jackson, MS - Atlanta, GABuses Jackson, MS - Shreveport, LABuses Jackson, MS - Tyler, TX

Other destinations from Jackson, MS

Buses Jackson, MS - Boston, MABuses Jackson, MS - Houston, TXBuses Jackson, MS - Atlanta, GABuses Jackson, MS - Phoenix, AZBuses Jackson, MS - Cincinnati, OHBuses Jackson, MS - Saint Paul, MNBuses Jackson, MS - Portland, MEBuses Jackson, MS - Baton Rouge, LABuses Jackson, MS - San Bernardino, CABuses Jackson, MS - Dallas, TXBuses Jackson, MS - Hattiesburg, MSBuses Jackson, MS - Oklahoma City, OK

Main routes to Chicago, IL

Buses San Diego, CA - Chicago, ILBuses Washington, DC - Chicago, ILBuses Austin, TX - Chicago, ILBuses Los Angeles, CA - Chicago, ILBuses Denver, CO - Chicago, ILBuses Detroit, MI - Chicago, ILBuses Buffalo, NY - Chicago, ILBuses Memphis, TN - Chicago, ILBuses Atlanta, GA - Chicago, ILBuses Houston, TX - Chicago, ILBuses Madison, WI - Chicago, ILBuses Dallas, TX - Chicago, IL

Related routes

Trains Jackson, MS - Chicago, IL

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